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Contact Us

For general inquiries about The Caroline Symmes Children’s Cancer Endowment, use our contact form and we’ll get back to you as soon as possible.

You can also reach out to us using the contact info below.

Frequently Asked Questions

The Caroline Symmes Children’s Cancer Endowment for Pediatric Cancer Research was created by David and Libby Symmes in memory of their daughter. Caroline was diagnosed with Wilms Tumor Disease a month before her fourth birthday. This type of cancer has an extremely high cure rate. But quickly, David and Libby learned that it didn’t matter the cure rate, that each cancer or tumor was unique to a child’s body, and that Caroline’s tumor was very aggressive. Over a 16 month period and after numerous treatments ranging from surgeries, chemotherapy, radiation and a stem cell transplant, Caroline passed away at the age of 5.

Our mission is to raise crucial funds to support cutting edge research by leading pediatric oncologists around the country as they create targeted drugs, less toxic therapies, and brighter outcomes for critically ill children.

Currently all donations, through fundraisers, partnerships and individual donors, goes to towards two Endowment funds. The initial fund supports researchers and the Precision Genomics team at Riley Children’s Health. The second endowed fund started in late 2020, supports researchers in a specific research lab at Riley Children’s Health, and they are searching for therapies and cures for all childhood cancers.

Caroline was treated at Riley Hospital for Children at Indiana University Health. When she lost her life at 5 years old, David and Libby Symmes knew they needed to do something because of the lack of funding for childhood cancers. In 2011 they created the Caroline Symmes Cancer Endowment and in 2014 became a 501(c)(3), with all donations going towards research taking place in labs at the hospital that cared for their daughter.

At the beginning of 2019, we sent out applications searching for high school students around Central Indiana who wanted to become involved with the Endowment by joining the inaugural Teen Board. We were overwhelmed when we received over 50 applications. Since then, each year we receive a high number of applications of very well-deserving high school students, who want to replace the graduating seniors and make a difference. After review of applications and interviews, the Endowment Leadership chooses new additions, while keeping the Teen Board to a size of 20-25 students. The representation has averaged between seven and ten surrounding high schools.


The Teen Board's key goals are to individually create peer-to-peer fundraising efforts; develop events, such as Runway for Riley, that the full board implements; marketing their efforts through social media avenues and selling Endowment merchandise.


Meet our current Teen Board here.

Our donations come from several sources: fundraisers, partnerships and individual donations.

We would love to have you host a fundraiser – big or small! You can view past fundraisers here. For help creating a fundraiser, we have a toolkit just for you!

As of late 2020, we have raised $3.3 million specifically for the Precision Genomics Program and the research of pediatric Non-CNS Solid tumors at Riley Children’s Health. In early 2021 we committed to raising $1.5 million for a newly established fund, which will be used to research all types of childhood cancers at Riley Hospital for Children at Indiana University Health.